PDBe 4f7t

X-ray diffraction
1.7Å resolution

Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PB1 (498-505)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
HLA class I histocompatibility antigen, A-24 alpha chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 275 amino acids
Theoretical weight: 31.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05534 (Residues: 25-298; Coverage: 80%)
Gene names: HLA-A, HLAA
Sequence domains:
Structure domains:
Beta-2-microglobulin Chains: B, E
Molecule details ›
Chains: B, E
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
RNA-directed RNA polymerase catalytic subunit Chains: C, F
Molecule details ›
Chains: C, F
Length: 8 amino acids
Theoretical weight: 974 Da
Source organism: Influenza A virus H3N2
Expression system: Not provided
UniProt:
  • Canonical: Q9YXL6 (Residues: 498-505; Coverage: 1%)
Gene name: PB1

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P1
Unit cell:
a: 52.838Å b: 66.583Å c: 70.362Å
α: 97.7° β: 101.03° γ: 111.84°
R-values:
R R work R free
0.197 0.196 0.227
Expression systems:
  • Escherichia coli
  • Not provided