PDBe 4e0o

X-ray diffraction
1.82Å resolution

SVQIVYK segment from human Tau (305-311) displayed on 54-membered macrocycle scaffold (form III)

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated protein tau Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 14 amino acids
Theoretical weight: 1.93 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10636 (Residues: 621-628; Coverage: 1%)
Gene names: MAPT, MAPTL, MTBT1, TAU

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 30.41Å b: 25.43Å c: 52.53Å
α: 90° β: 91.19° γ: 90°
R-values:
R R work R free
0.184 0.182 0.229
Expression system: Not provided