PDBe 4duu

X-ray diffraction
5.2Å resolution

The X-ray Crystal Structure of Full-Length type I Human Plasminogen

Released:

Function and Biology Details

Reaction catalysed:
Preferential cleavage: Lys-|- > Arg-|-; higher selectivity than trypsin. Converts fibrin into soluble products.

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plasminogen Chain: A
Molecule details ›
Chain: A
Length: 791 amino acids
Theoretical weight: 88.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: NEW P00747 (Residues: 20-810; Coverage: 100%)
Gene name: PLG
Sequence domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P43212
Unit cell:
a: 110.12Å b: 110.12Å c: 234.815Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.27 0.268 0.312