PDBe 4dur

X-ray diffraction
2.45Å resolution

The X-ray Crystal Structure of Full-Length type II Human Plasminogen

Released:

Function and Biology Details

Reaction catalysed:
Preferential cleavage: Lys-|- > Arg-|-; higher selectivity than trypsin. Converts fibrin into soluble products.

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plasminogen Chains: A, B
Molecule details ›
Chains: A, B
Length: 791 amino acids
Theoretical weight: 88.54 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P00747 (Residues: 20-810; Coverage: 100%)
Gene name: PLG
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX2
Spacegroup: P3221
Unit cell:
a: 144.62Å b: 144.62Å c: 233.67Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.191 0.19 0.216