PDBe 4d0e

X-ray diffraction
1.61Å resolution

Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neurogenic locus notch homolog protein 1 Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 14.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P46531 (Residues: 411-526; Coverage: 5%)
Gene names: NOTCH1, TAN1
Sequence domains:
Structure domains: Laminin

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04-1
Spacegroup: P3121
Unit cell:
a: 28.44Å b: 28.44Å c: 282.39Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.232 0.231 0.27
Expression system: Escherichia coli