PDBe 4cxj

X-ray diffraction
2.8Å resolution

BTB domain of KEAP1 C151W mutant

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kelch-like ECH-associated protein 1 Chain: A
Molecule details ›
Chain: A
Length: 137 amino acids
Theoretical weight: 15.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q14145 (Residues: 48-180; Coverage: 21%)
Gene names: INRF2, KEAP1, KIAA0132, KLHL19
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P6522
Unit cell:
a: 42.874Å b: 42.874Å c: 267.637Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.215 0.211 0.271
Expression system: Escherichia coli BL21(DE3)