PDBe 4ct0

X-ray diffraction
2.45Å resolution

Crystal Structure of Mouse Cryptochrome1 in Complex with Period2

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cryptochrome-1 Chain: A
Molecule details ›
Chain: A
Length: 507 amino acids
Theoretical weight: 58.5 KDa
Source organism: Mus musculus
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P97784 (Residues: 1-496; Coverage: 82%)
Gene name: Cry1
Sequence domains:
Structure domains:
Period circadian protein homolog 2 Chain: B
Molecule details ›
Chain: B
Length: 143 amino acids
Theoretical weight: 16.32 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O54943 (Residues: 1132-1252; Coverage: 10%)
Gene name: Per2

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P43212
Unit cell:
a: 99.736Å b: 99.736Å c: 178.632Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.186 0.233
Expression systems:
  • Trichoplusia ni
  • Escherichia coli BL21(DE3)