PDBe 4c4k

X-ray diffraction
1.95Å resolution

Crystal structure of the titin M10-Obscurin Ig domain 1 complex

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Obscurin Chain: O
Molecule details ›
Chain: O
Length: 98 amino acids
Theoretical weight: 10.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5VST9 (Residues: 9-103; Coverage: 1%)
Gene names: KIAA1556, KIAA1639, OBSCN
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins
Titin Chain: T
Molecule details ›
Chain: T
Length: 102 amino acids
Theoretical weight: 10.98 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8WZ42 (Residues: 34252-34350; Coverage: 0%)
Gene name: TTN
Sequence domains: Immunoglobulin I-set domain
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P212121
Unit cell:
a: 40.94Å b: 66.88Å c: 72.93Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.171 0.21
Expression system: Escherichia coli BL21(DE3)