PDBe 4bry

X-ray diffraction
2.89Å resolution

The Idas:Geminin heterodimeric parallel coiled-coil

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Geminin Chain: A
Molecule details ›
Chain: A
Length: 78 amino acids
Theoretical weight: 9.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O75496 (Residues: 83-160; Coverage: 37%)
Gene name: GMNN
Structure domains: Geminin coiled-coil domain
Multicilin Chain: B
Molecule details ›
Chain: B
Length: 73 amino acids
Theoretical weight: 8.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: D6RGH6 (Residues: 173-245; Coverage: 19%)
Gene names: IDAS, MCI, MCIDAS, MCIN
Structure domains: Geminin coiled-coil domain

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: I4122
Unit cell:
a: 117.799Å b: 117.799Å c: 103.462Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.203 0.226
Expression system: Escherichia coli BL21