PDBe 4bqd

X-ray diffraction
2.48Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tissue factor pathway inhibitor Chains: A, B
Molecule details ›
Chains: A, B
Length: 79 amino acids
Theoretical weight: 9.28 KDa
Source organism: Homo sapiens
  • Canonical: P10646 (Residues: 29-107; Coverage: 29%)
Gene names: LACI, TFPI, TFPI1
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain
PEPTIDE Chains: C, D
Molecule details ›
Chains: C, D
Length: 21 amino acids
Theoretical weight: 2.36 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 113.67Å b: 69.32Å c: 42.37Å
α: 90° β: 92.97° γ: 90°
R R work R free
0.228 0.227 0.262
Expression system: Not provided