PDBe 4bj3

X-ray diffraction
3.04Å resolution

Integrin alpha2 I domain E318W-collagen complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin alpha-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 225 amino acids
Theoretical weight: 25.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P17301 (Residues: 171-368; Coverage: 17%)
Gene names: CD49B, ITGA2
Sequence domains: von Willebrand factor type A domain
Structure domains: von Willebrand factor, type A domain
Collagen alpha-1(XXVI) chain Chains: C, D, E
Molecule details ›
Chains: C, D, E
Length: 21 amino acids
Theoretical weight: 2.02 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q96A83 (Residues: 308-328; Coverage: 5%)
Gene names: COL26A1, EMID2, EMU2

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: P43212
Unit cell:
a: 83.004Å b: 83.004Å c: 175.256Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.251 0.246 0.298
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided