PDBe 4ajk

X-ray diffraction
2.03Å resolution

rat LDHA in complex with N-(2-(methylamino)-1,3-benzothiazol-6-yl) acetamide


Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
L-lactate dehydrogenase A chain Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 331 amino acids
Theoretical weight: 36.36 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P04642 (Residues: 2-332; Coverage: 100%)
Gene names: Ldh-1, Ldh1, Ldha
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P21
Unit cell:
a: 62.174Å b: 81.749Å c: 128.975Å
α: 90° β: 96.14° γ: 90°
R R work R free
0.15 0.147 0.19
Expression system: Escherichia coli BL21(DE3)