PDBe 4aj1

X-ray diffraction
1.87Å resolution

rat LDHA in complex with N-(2-(methylamino)-1,3-benzothiazol-6-yl) acetamide

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
L-lactate dehydrogenase A chain Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 331 amino acids
Theoretical weight: 36.36 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04642 (Residues: 2-332; Coverage: 100%)
Gene names: Ldh-1, Ldh1, Ldha
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E
Spacegroup: P21
Unit cell:
a: 62.241Å b: 81.914Å c: 128.869Å
α: 90° β: 96.18° γ: 90°
R-values:
R R work R free
0.176 0.173 0.231
Expression system: Escherichia coli BL21(DE3)