PDBe 3znc

X-ray diffraction
2.8Å resolution

MURINE CARBONIC ANHYDRASE IV COMPLEXED WITH BRINZOLAMIDE

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 4 Chain: A
Molecule details ›
Chain: A
Length: 258 amino acids
Theoretical weight: 29.49 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q64444 (Residues: 22-279; Coverage: 90%)
Gene names: Ca4, Car4
Structure domains: Carbonic Anhydrase II

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: C2221
Unit cell:
a: 53.5Å b: 85.2Å c: 121.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.191 0.191 0.277
Expression system: Escherichia coli