Function and Biology

Crystal structure of Bcl-xL in complex with inhibitor (Compound 3).

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of apoptotic process
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00452
Domain description: Apoptosis regulator proteins, Bcl-2 family
Occurring in:
  1. Bcl-2-like protein 1
1 copy of Pfam domain PF00452 (Apoptosis regulator proteins, Bcl-2 family) in Bcl-2-like protein 1 in PDB 3zln.

PF02180
Domain description: Bcl-2 homology region 4
Occurring in:
  1. Bcl-2-like protein 1
1 copy of Pfam domain PF02180 (Bcl-2 homology region 4) in Bcl-2-like protein 1 in PDB 3zln.

InterPro InterPro annotations
IPR026298
Domain description: Blc2 family
Occurring in:
  1. Bcl-2-like protein 1
IPR013279
Domain description: Apoptosis regulator, Bcl-X
Occurring in:
  1. Bcl-2-like protein 1
IPR036834
Domain description: Blc2-like superfamily
Occurring in:
  1. Bcl-2-like protein 1
IPR003093
Domain description: Apoptosis regulator, Bcl-2 protein, BH4
Occurring in:
  1. Bcl-2-like protein 1
IPR020728
Domain description: Apoptosis regulator, Bcl-2, BH3 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1
IPR020726
Domain description: Apoptosis regulator, Bcl-2, BH2 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1
IPR020717
Domain description: Apoptosis regulator, Bcl-2, BH1 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1
IPR002475
Domain description: Bcl2-like
Occurring in:
  1. Bcl-2-like protein 1
IPR020731
Domain description: Apoptosis regulator, Bcl-2, BH4 motif, conserved site
Occurring in:
  1. Bcl-2-like protein 1