› 3x0g

X-ray diffraction
1.9Å resolution

Crystal structure of the ectodomain of African green monkey CD81 large extracellular loop (agmCD81-LEL)

Released:
DOI: 10.2210/pdb3x0g/pdb
PDB entry 3x0g coloured by chain, front view.
PDB entry 3x0g coloured by chain, side view.
PDB entry 3x0g coloured by chain, top view.
Source organism: Chlorocebus sabaeus
Primary publication:
An intramolecular bond at cluster of differentiation 81 ectodomain is important for hepatitis C virus entry.
Yang W, Zhang M, Chi X, Liu X, Qin B, Cui S
FASEB J 29 4214-26 (2015)
PMID: 26116703

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetraspanin Chain: A
Molecule details ›
Chain: A
Length: 93 amino acids
Theoretical weight: 10.2 KDa
Source organism: Chlorocebus sabaeus
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0D9RBI8 (Residues: 113-202; Coverage: 38%)
Gene name: CD81
Sequence domains: Tetraspanin family
Structure domains: Tetraspanin

Ligands and Environments

1 bound ligand:
Ligand MPD 3 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Unit cell:
a: 39.156Å b: 39.7Å c: 59.915Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.231 0.254
Expression system: Escherichia coli

Quick links

Citations

4 citation in other articles

Oligomerization of the Tetraspanin CD81 via the Flexibility of Its δ-Loop.
Schmidt et al. (2016)
3 more