PDBe 3wu0

X-ray diffraction
2.6Å resolution

Crystal structure of phosphorylated ETS-1 DNA binding and autoinhibitory domains (276-441)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein C-ets-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 166 amino acids
Theoretical weight: 19.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P14921 (Residues: 276-441; Coverage: 38%)
Gene names: ETS1, EWSR2
Sequence domains: Ets-domain
Structure domains: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: P31
Unit cell:
a: 56.71Å b: 56.71Å c: 105.984Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.222 0.222 0.277
Expression system: Escherichia coli