› › Function and Biology

Crystal structure of the Archaeoglobus fulgidus oligosaccharyltransferase (O29867_ARCFU) in the apo form

Source organism: Archaeoglobus fulgidus DSM 4304
Biochemical function: metal ion binding
Biological process: post-translational protein modification
Cellular component: membrane

Quick links

EC 2.4.99.21: Dolichyl-phosphooligosaccharide-protein glycotransferase

Reaction catalysed:
An archaeal dolichyl phosphooligosaccharide + [protein]-L-asparagine = an archaeal dolichyl phosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine
Systematic name:
Dolichyl-phosphooligosaccharide:protein-L-asparagine N-beta-D-oligosaccharidotransferase
Alternative Name(s):
  • AglB
  • Archaeal oligosaccharyl transferase
  • Dolichyl-monophosphooligosaccharide-protein glycotransferase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF18079
Domain description: Archaeal glycosylation protein B long peripheral domain
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3
The deposited structure of PDB entry 3wak contains 1 copy of Pfam domain PF18079 (Archaeal glycosylation protein B long peripheral domain) in Dolichyl-phosphooligosaccharide-protein glycotransferase 3. Showing 1 copy in chain A.

PF02516
Domain description: Oligosaccharyl transferase STT3, N-terminal
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3
The deposited structure of PDB entry 3wak contains 1 copy of Pfam domain PF02516 (Oligosaccharyl transferase STT3, N-terminal) in Dolichyl-phosphooligosaccharide-protein glycotransferase 3. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR003674
Domain description: Oligosaccharyl transferase, STT3 subunit
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3
IPR041154
Domain description: Archaeal glycosylation protein B, peripheral domain
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3
IPR026410
Domain description: Oligosaccharyl transferase, archaeal
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3

Structure domains

CATH CATH domains
3.40.50.12610
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3
The deposited structure of PDB entry 3wak contains 1 copy of CATH domain 3.40.50.12610 (Rossmann fold) in Dolichyl-phosphooligosaccharide-protein glycotransferase 3. Showing 1 copy in chain A.
1.20.58.1650
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3
The deposited structure of PDB entry 3wak contains 1 copy of CATH domain 1.20.58.1650 (Methane Monooxygenase Hydroxylase; Chain G, domain 1) in Dolichyl-phosphooligosaccharide-protein glycotransferase 3. Showing 1 copy in chain A.
2.60.40.3390
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulin-like
Occurring in:
  1. Dolichyl-phosphooligosaccharide-protein glycotransferase 3
The deposited structure of PDB entry 3wak contains 1 copy of CATH domain 2.60.40.3390 (Immunoglobulin-like) in Dolichyl-phosphooligosaccharide-protein glycotransferase 3. Showing 1 copy in chain A.

Quick links