Function and Biology

Crystal structures of rat VDR-LBD with R270L mutation

Source organisms:
Biochemical function: DNA binding
Biological process: steroid hormone mediated signaling pathway
Cellular component: nucleus

Sequence family

CATH Protein family (Pfam)
PF00104
Domain description: Ligand-binding domain of nuclear hormone receptor
Occurring in:
  1. Vitamin D3 receptor
1 copy of Pfam domain PF00104 (Ligand-binding domain of nuclear hormone receptor) in Vitamin D3 receptor in PDB 3vt5.

CATH InterPro annotations
IPR001728
Domain description: Thyroid hormone receptor
Occurring in:
  1. Vitamin D3 receptor
IPR001723
Domain description: Nuclear hormone receptor
Occurring in:
  1. Vitamin D3 receptor
IPR000536
Domain description: Nuclear hormone receptor, ligand-binding domain
Occurring in:
  1. Vitamin D3 receptor

Structure domain

CATH CATH domain
1.10.565.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Retinoid X Receptor
Homology: Retinoid X Receptor
Occurring in:
  1. Vitamin D3 receptor