PDBe 3vhv

X-ray diffraction
1.35Å resolution

Mineralocorticoid receptor ligand-binding domain with non-steroidal antagonist

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mineralocorticoid receptor Chain: A
Molecule details ›
Chain: A
Length: 260 amino acids
Theoretical weight: 30.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08235 (Residues: 727-984; Coverage: 26%)
Gene names: MCR, MLR, NR3C2
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.3
Spacegroup: P32
Unit cell:
a: 62.612Å b: 62.612Å c: 75.504Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.142 0.141 0.167
Expression system: Escherichia coli