› › Structure analysis

1E6-A*0201-ALWGPDPAAA Complex, Monoclinic

X-ray diffraction
2.712Å resolution
PDB entry 3uts coloured by chain, front view.
PDB entry 3uts coloured by chain, side view.
PDB entry 3uts coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero pentamer (preferred)
Entry contents: 5 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1
Download    3D Visualisation
Assembly Name: Insulin complex
hide full assembly name
Multimeric state: hetero pentamer
Accessible surface area: 39936.83 Å2
Buried surface area: 10536.1 Å2
Dissociation area: 782.38 Å2
Dissociation energy (ΔGdiss): -5.05 kcal/mol
Dissociation entropy (TΔSdiss): 13.83 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-208404
Assembly 2 (preferred)
Download    3D Visualisation
Assembly Name: Insulin complex
hide full assembly name
Multimeric state: hetero pentamer
Accessible surface area: 39648.07 Å2
Buried surface area: 10757.6 Å2
Dissociation area: 1,309.28 Å2
Dissociation energy (ΔGdiss): 5.42 kcal/mol
Dissociation entropy (TΔSdiss): 12.33 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-208404

Macromolecules

HLA class I histocompatibility antigen, A alpha chain
Chains: A, F
Length: 276 amino acids
Theoretical weight: 31.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P04439 (Residues: 25-299; Coverage: 81%)
Gene names: HLA-A, HLAA
Pfam:
InterPro:
CATH:
HLA class I histocompatibility antigen, A alpha chain in PDB entry 3uts, assembly 2, front view.
HLA class I histocompatibility antigen, A alpha chain in PDB entry 3uts, assembly 2, side view.
HLA class I histocompatibility antigen, A alpha chain in PDB entry 3uts, assembly 2, top view.
Molecule details ›

Search similar proteins

Beta-2-microglobulin
Chains: B, G
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
Beta-2-microglobulin in PDB entry 3uts, assembly 2, front view.
Beta-2-microglobulin in PDB entry 3uts, assembly 2, side view.
Beta-2-microglobulin in PDB entry 3uts, assembly 2, top view.
Molecule details ›

Search similar proteins

Insulin
Chains: C, H
Length: 10 amino acids
Theoretical weight: 968 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01308 (Residues: 15-24; Coverage: 0%)
Gene name: INS
Insulin in PDB entry 3uts, assembly 2, front view.
Insulin in PDB entry 3uts, assembly 2, side view.
Insulin in PDB entry 3uts, assembly 2, top view.
Molecule details ›

Search similar proteins

1E6 TCR Alpha Chain
Chains: D, I
Length: 201 amino acids
Theoretical weight: 22.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
InterPro:
CATH: Immunoglobulins
1E6 TCR Alpha Chain in PDB entry 3uts, assembly 2, front view.
1E6 TCR Alpha Chain in PDB entry 3uts, assembly 2, side view.
1E6 TCR Alpha Chain in PDB entry 3uts, assembly 2, top view.
Molecule details ›

Search similar proteins

1E6 TCR Beta Chain
Chains: E, J
Length: 246 amino acids
Theoretical weight: 28.03 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
InterPro:
CATH: Immunoglobulins
1E6 TCR Beta Chain in PDB entry 3uts, assembly 2, front view.
1E6 TCR Beta Chain in PDB entry 3uts, assembly 2, side view.
1E6 TCR Beta Chain in PDB entry 3uts, assembly 2, top view.
Molecule details ›

Search similar proteins

Quick links