EC 2.7.11.4: [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase
Reaction catalysed:
ATP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] = ADP + [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] phosphate
Systematic name:
ATP:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] phosphotransferase
Alternative Name(s):
- BCK
- BCKD kinase
- BCODH kinase
- Branched-chain 2-oxo acid dehydrogenase kinase
- Branched-chain alpha-ketoacid dehydrogenase kinase
- Branched-chain keto acid dehydrogenase kinase
- Branched-chain oxo acid dehydrogenase kinase (phosphorylating)
- STK2
EC 2.7.11.1: Non-specific serine/threonine protein kinase
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (non-specific)
Alternative Name(s):
- A-kinase
- AP50 kinase
- ATP-protein transphosphorylase
- Beta-IIPKC
- Beta-adrenergic receptor kinase
- CK-2
- CKI
- CKII
- Calcium-dependent protein kinase C
- Calcium/phospholipid-dependent protein kinase
- Casein kinase
- Casein kinase (phosphorylating)
- Casein kinase 2
- Casein kinase I
- Casein kinase II
- Cyclic AMP-dependent protein kinase
- Cyclic AMP-dependent protein kinase A
- Cyclic monophosphate-dependent protein kinase
- Cyclic nucleotide-dependent protein kinase
- Cyclin-dependent kinase
- Cytidine 3',5'-cyclic monophosphate-responsive protein kinase
- Dsk1
- Epsilon PKC
- Glycogen synthase A kinase
- Glycogen synthase a kinase
- Glycogen synthase kinase
- HIPK2
- Hpr kinase
- Hydroxyalkyl-protein kinase
- M phase-specific cdc2 kinase
- MAPK
- Mitogen-activated S6 kinase
- Mitogen-activated protein kinase
- P82 kinase
- PKA
- PKC
- Phosphorylase B kinase kinase
- Phosphorylase b kinase kinase
- Phosphorylase b kinase kinase
- Protein glutamyl kinase
- Protein kinase (phosphorylating)
- Protein kinase A
- Protein kinase CK2
- Protein kinase p58
- Protein phosphokinase
- Protein serine kinase
- Protein serine-threonine kinase
- Protein-aspartyl kinase
- Protein-cysteine kinase
- Protein-serine kinase
- Prp4 protein kinase
- Raf kinase
- Raf-1
- Ribosomal S6 protein kinase
- Ribosomal protein S6 kinase II
- STK32
- Serine kinase
- Serine protein kinase
- Serine(threonine) protein kinase
- Serine-specific protein kinase
- Serine/threonine protein kinase
- T-antigen kinase
- Threonine-specific protein kinase
- Twitchin kinase
- Type-2 casein kinase
- WEE1Hu
- Wee 1-like kinase
- Wee-kinase
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase A
- cGMP-dependent protein kinase
GO terms
Biochemical function:
- protein serine kinase activity
- [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity
- transferase activity, transferring phosphorus-containing groups
- transferase activity
- kinase activity
- ATP binding
- pyruvate dehydrogenase (acetyl-transferring) kinase activity
- protein serine/threonine phosphatase activity
- protein serine/threonine kinase activity
- protein kinase activity
- nucleotide binding
Biological process:
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
IPR004358
Domain description:
Signal transduction histidine kinase-related protein, C-terminal
Occurring in:
Occurring in:
IPR036784
Domain description:
Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily
Occurring in:
Occurring in:
IPR018955
Domain description:
Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal
Occurring in:
Occurring in:
Structure domains
CATH domains
3.30.565.10
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
Heat Shock Protein 90
Homology:
Histidine kinase-like ATPase, C-terminal domain
Occurring in:
