PDBe 3tz0

X-ray diffraction
2.5Å resolution

Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/S-alpha-chloroisocaproate complex

Released:

Function and Biology Details

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 418 amino acids
Theoretical weight: 47.37 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00972 (Residues: 1-412; Coverage: 100%)
Gene name: Bckdk
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P42212
Unit cell:
a: 128.801Å b: 128.801Å c: 72.914Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.204 0.24
Expression system: Escherichia coli