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Structural basis for Discs Large interaction with Pins

Source organism: Drosophila melanogaster
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF00625
Domain description: Guanylate kinase
Occurring in:
  1. Disks large 1 tumor suppressor protein
The deposited structure of PDB entry 3tvt contains 1 copy of Pfam domain PF00625 (Guanylate kinase) in Disks large 1 tumor suppressor protein. Showing 1 copy in chain A.

PF00018
Domain description: SH3 domain
Occurring in:
  1. Disks large 1 tumor suppressor protein
The deposited structure of PDB entry 3tvt contains 1 copy of Pfam domain PF00018 (SH3 domain) in Disks large 1 tumor suppressor protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001452
Domain description: SH3 domain
Occurring in:
  1. Disks large 1 tumor suppressor protein
IPR008145
Domain description: Guanylate kinase/L-type calcium channel beta subunit
Occurring in:
  1. Disks large 1 tumor suppressor protein
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Disks large 1 tumor suppressor protein
IPR020590
Domain description: Guanylate kinase, conserved site
Occurring in:
  1. Disks large 1 tumor suppressor protein
IPR008144
Domain description: Guanylate kinase-like domain
Occurring in:
  1. Disks large 1 tumor suppressor protein
IPR036028
Domain description: SH3-like domain superfamily
Occurring in:
  1. Disks large 1 tumor suppressor protein

Structure domains

CATH CATH domains
2.30.30.40
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 Domains
Occurring in:
  1. Disks large 1 tumor suppressor protein
The deposited structure of PDB entry 3tvt contains 1 copy of CATH domain 2.30.30.40 (SH3 type barrels.) in Disks large 1 tumor suppressor protein. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. Disks large 1 tumor suppressor protein
The deposited structure of PDB entry 3tvt contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in Disks large 1 tumor suppressor protein. Showing 1 copy in chain A.
3.30.63.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Guanylate Kinase phosphate binding domain
Homology: Guanylate Kinase phosphate binding domain
Occurring in:
  1. Disks large 1 tumor suppressor protein
The deposited structure of PDB entry 3tvt contains 1 copy of CATH domain 3.30.63.10 (Guanylate Kinase phosphate binding domain) in Disks large 1 tumor suppressor protein. Showing 1 copy in chain A.

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