PDBe 3tvn

X-ray diffraction
1.5Å resolution

Human Carbonic Anhydrase II Proton Transfer Mutant

Released:

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Carbonic anhydrase 2 Chain: X
Molecule details ›
Chain: X
Length: 258 amino acids
Theoretical weight: 29.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P00918 (Residues: 3-260; Coverage: 99%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Carbonic Anhydrase II

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 42.005Å b: 41.223Å c: 72.059Å
α: 90° β: 104.32° γ: 90°
R-values:
R R work R free
0.177 0.176 0.211
Expression system: Escherichia coli BL21