Function and Biology

Crystal structure of the stable degradation fragment of human plakophilin 2 isoform a (PKP2a) C752R variant

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: cell-cell adhesion
Cellular component: not assigned

GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00514
Domain description: Armadillo/beta-catenin-like repeat
Occurring in:
  1. Plakophilin-2
The deposited structure of PDB entry 3tt9 contains 2 copies of Pfam domain PF00514 (Armadillo/beta-catenin-like repeat) in Plakophilin-2. Showing 2 copies in chain A.

InterPro InterPro annotations
IPR000225
Domain description: Armadillo
Occurring in:
  1. Plakophilin-2
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Plakophilin-2
IPR028435
Domain description: Plakophilin/Delta catenin
Occurring in:
  1. Plakophilin-2
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Plakophilin-2

Structure domain

CATH CATH domain
1.25.10.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Leucine-rich Repeat Variant
Homology: Leucine-rich Repeat Variant
Occurring in:
  1. Plakophilin-2
The deposited structure of PDB entry 3tt9 contains 1 copy of CATH domain 1.25.10.10 (Leucine-rich Repeat Variant) in Plakophilin-2. Showing 1 copy in chain A.