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human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii

Source organisms:
Biochemical function: actin filament binding
Biological process: cell adhesion
Cellular component: actin cytoskeleton

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GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF01044
Domain description: Vinculin family
Occurring in:
  1. Vinculin

InterPro InterPro annotations
IPR000633
Domain description: Vinculin, conserved site
Occurring in:
  1. Vinculin
IPR036723
Domain description: Alpha-catenin/vinculin-like superfamily
Occurring in:
  1. Vinculin
IPR006077
Domain description: Vinculin/alpha-catenin
Occurring in:
  1. Vinculin
IPR017997
Domain description: Vinculin
Occurring in:
  1. Vinculin

Structure domain

CATH CATH domain
1.20.120.230
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology: Alpha-catenin/vinculin-like
Occurring in:
  1. Vinculin
The deposited structure of PDB entry 3tj5 contains 2 copies of CATH domain 1.20.120.230 (Four Helix Bundle (Hemerythrin (Met), subunit A)) in Vinculin. Showing 2 copies in chain A.

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