› 3t6n

X-ray diffraction
2.31Å resolution

Crystal Structure of Transcriptional Regulator

Released:
DOI: 10.2210/pdb3t6n/pdb
PDB entry 3t6n coloured by chain, front view.
PDB entry 3t6n coloured by chain, side view.
PDB entry 3t6n coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Entry authors: Do SV, Bolla JR, Chen X, Yu EW

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125178 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 208 amino acids
Theoretical weight: 22.82 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli
UniProt:
  • Canonical: I6X658 (Residues: 1-202; Coverage: 100%)
Gene name: Rv3066
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P21212
Unit cell:
a: 78.699Å b: 118.866Å c: 42.137Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.203 0.271
Expression system: Escherichia coli

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