PDBe 3sem

X-ray diffraction
2.2Å resolution

SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SH3 PEPTOID INHIBITOR Chains: C, D
Molecule details ›
Chains: C, D
Length: 9 amino acids
Theoretical weight: 1.09 KDa
Source organism: Synthetic construct
Expression system: Not provided
Sex muscle abnormal protein 5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 60 amino acids
Theoretical weight: 7 KDa
Source organism: Caenorhabditis elegans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29355 (Residues: 155-214; Coverage: 26%)
Gene names: C14F5.5, sem-5
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21
Unit cell:
a: 27.05Å b: 68.53Å c: 35.02Å
α: 90° β: 93.86° γ: 90°
R-values:
R R work R free
0.248 0.248 0.31
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)