PDBe 3s0z

X-ray diffraction
2.5Å resolution

Crystal structure of New Delhi Metallo-beta-lactamase (NDM-1)

Released:
Source organism: Escherichia coli

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallo-beta-lactamase NDM-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 224 amino acids
Theoretical weight: 23.58 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: E5KIY2 (Residues: 47-270; Coverage: 83%)
Gene names: AM375_01085, APU18_05360, AZ95_0035, BET08_16280, CA268_28970, ECS01_0033, MS6198_A142, NDM1Dok01_N0175, bla NDM-1, blaNDM-1, pNDM102337_147, pNDM10505_149
Sequence domains: Metallo-beta-lactamase superfamily
Structure domains: Metallo-beta-lactamase, chain A

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: P31
Unit cell:
a: 40.696Å b: 40.696Å c: 215.292Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.236 0.234 0.267
Expression system: Escherichia coli