PDBe 3rzf

X-ray diffraction
4Å resolution

Crystal Structure of Inhibitor of kappaB kinase beta (I4122)

Released:
Source organism: Xenopus laevis
Primary publication:
Crystal structure of inhibitor of κB kinase β.
OpenAccess logo Nature 472 325-30 (2011)
PMID: 21423167

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MGC80376 protein Chain: A
Molecule details ›
Chain: A
Length: 677 amino acids
Theoretical weight: 78 KDa
Source organism: Xenopus laevis
UniProt:
  • Canonical: Q6INT1 (Residues: 1-659; Coverage: 89%)
Gene names: MGC80376, ikbkb
Sequence domains: Protein kinase domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: I4122
Unit cell:
a: 164.656Å b: 164.656Å c: 273.458Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.273 0.27 0.34