PDBe 3qp6

X-ray diffraction
2Å resolution

Crystal structure of CviR (Chromobacterium violaceum 12472) bound to C6-HSL

Source organism: Chromobacterium violaceum
Primary publication:
A strategy for antagonizing quorum sensing.
Mol. Cell 42 199-209 (2011)
PMID: 21504831

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Transcriptional activator, LuxR/UhpA family of regulators Chain: A
Molecule details ›
Chain: A
Length: 265 amino acids
Theoretical weight: 29.56 KDa
Source organism: Chromobacterium violaceum
Expression system: Escherichia coli BL21(DE3)
  • Canonical: NEW Q7NQP7 (Residues: 1-265; Coverage: 100%)
Gene names: CV_4090, cviR
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2221
Unit cell:
a: 50.248Å b: 89.12Å c: 132.125Å
α: 90° β: 90° γ: 90°
R R work R free
0.185 0.183 0.224
Expression system: Escherichia coli BL21(DE3)