PDBe 3qp5

X-ray diffraction
3.25Å resolution

Crystal structure of CviR bound to antagonist chlorolactone (CL)

Released:
Source organism: Chromobacterium violaceum
Primary publication:
A strategy for antagonizing quorum sensing.
Mol. Cell 42 199-209 (2011)
PMID: 21504831

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CviR transcriptional regulator Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 265 amino acids
Theoretical weight: 29.75 KDa
Source organism: Chromobacterium violaceum
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: NEW D3W065 (Residues: 1-265; Coverage: 100%)
Gene names: CLV04_3159, cviR
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: R3
Unit cell:
a: 169.318Å b: 169.318Å c: 99.844Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.265 0.263 0.304
Expression system: Escherichia coli BL21(DE3)