PDBe 3qaq

X-ray diffraction
2.9Å resolution

Crystal structure of PI3K-gamma in complex with triazine-benzimidazole 1


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Chain: A

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 5.0.2
Spacegroup: C2
Unit cell:
a: 145.395Å b: 68.579Å c: 106.501Å
α: 90° β: 94.69° γ: 90°
R R work R free
0.22 0.217 0.265
Expression system: Spodoptera frugiperda