PDBe 3qag

X-ray diffraction
2Å resolution

Human Glutathione Transferase O2 with glutathione -new crystal form

Released:

Function and Biology Details

Reactions catalysed:
2 glutathione + dehydroascorbate = glutathione disulfide + ascorbate. 
RX + glutathione = HX + R-S-glutathione. 
Methylarsonate + 2 glutathione = methylarsonite + glutathione disulfide + H(2)O. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase omega-2 Chain: A
Molecule details ›
Chain: A
Length: 239 amino acids
Theoretical weight: 27.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H4Y5 (Residues: 1-239; Coverage: 98%)
Gene name: GSTO2
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P6522
Unit cell:
a: 53.138Å b: 53.138Å c: 352.4Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.226 0.224 0.265
Expression system: Escherichia coli