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Crystal Structure of P Domain from Norwalk Virus Strain Vietnam 026 in complex with disordered HBGA type Lex

X-ray diffraction
1.4Å resolution
PDB entry 3q6r coloured by chain, front view.
PDB entry 3q6r coloured by chain, side view.
PDB entry 3q6r coloured by chain, top view.
Source organism: Norwalk virus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Capsid protein
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Multimeric state: homo dimer
Accessible surface area: 23573.79 Å2
Buried surface area: 9432.83 Å2
Dissociation area: 3,404.42 Å2
Dissociation energy (ΔGdiss): -28.26 kcal/mol
Dissociation entropy (TΔSdiss): 14.35 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-177037

Macromolecules

Capsid protein
Chains: A, B
Length: 319 amino acids
Theoretical weight: 34.8 KDa
Source organism: Norwalk virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5F4T5 (Residues: 224-538; Coverage: 58%)
Pfam: Calicivirus coat protein C-terminal
InterPro: Calicivirus coat protein C-terminal
CATH:
Capsid protein in PDB entry 3q6r, assembly 1, front view.
Capsid protein in PDB entry 3q6r, assembly 1, side view.
Capsid protein in PDB entry 3q6r, assembly 1, top view.
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