PDBe 3q6m

X-ray diffraction
3Å resolution

Crystal Structure of Human MC-HSP90 in C2221 Space Group

Released:
Source organism: Homo sapiens
Primary publication:
The hexameric structures of human heat shock protein 90.
OpenAccess logo PLoS ONE 6 e19961 (2011)
PMID: 21647436

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock protein HSP 90-alpha Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 448 amino acids
Theoretical weight: 52.37 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07900 (Residues: 293-732; Coverage: 60%)
Gene names: HSP90A, HSP90AA1, HSPC1, HSPCA
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NW12A
Spacegroup: C2221
Unit cell:
a: 162.702Å b: 304.553Å c: 87.624Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.209 0.252
Expression system: Escherichia coli