PDBe 3q29

X-ray diffraction
2.3Å resolution

Cyrstal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP)


Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Maltose-binding periplasmic protein; Alpha-synuclein Chains: A, C
Molecule details ›
Chains: A, C
Length: 390 amino acids
Theoretical weight: 42.7 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: P37840 (Residues: 1-12, 13-19; Coverage: 14%)
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
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Gene names: JW3994, NACP, PARK1, SNCA, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 68.39Å b: 117.47Å c: 146.49Å
α: 90° β: 90° γ: 90°
R R work R free
0.194 0.193 0.232
Expression system: Escherichia coli