PDBe 3q28

X-ray diffraction
1.6Å resolution

Cyrstal structure of human alpha-synuclein (58-79) fused to maltose binding protein (MBP)


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Maltose-binding periplasmic protein; Alpha-synuclein Chain: A
Molecule details ›
Chain: A
Length: 393 amino acids
Theoretical weight: 42.9 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: P37840 (Residues: 58-69, 70-79; Coverage: 16%)
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
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Gene names: JW3994, NACP, PARK1, SNCA, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 57.54Å b: 48.57Å c: 57.85Å
α: 90° β: 94.23° γ: 90°
R R work R free
0.153 0.152 0.173
Expression system: Escherichia coli