PDBe 3q27

X-ray diffraction
1.3Å resolution

Cyrstal structure of human alpha-synuclein (32-57) fused to maltose binding protein (MBP)


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Maltose-binding periplasmic protein; Alpha-synuclein Chain: A
Molecule details ›
Chain: A
Length: 397 amino acids
Theoretical weight: 43.43 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: P37840 (Residues: 32-43, 44-57; Coverage: 19%)
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
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Gene names: JW3994, NACP, PARK1, SNCA, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P21
Unit cell:
a: 57.511Å b: 49.951Å c: 59.342Å
α: 90° β: 92.19° γ: 90°
R R work R free
0.132 0.131 0.156
Expression system: Escherichia coli