PDBe 3q26

X-ray diffraction
1.54Å resolution

Cyrstal structure of human alpha-synuclein (10-42) fused to maltose binding protein (MBP)


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Maltose-binding periplasmic protein; Alpha-synuclein Chain: A
Molecule details ›
Chain: A
Length: 404 amino acids
Theoretical weight: 44.02 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: P37840 (Residues: 10-21, 22-42; Coverage: 24%)
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
  • nullnull
Gene names: JW3994, NACP, PARK1, SNCA, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P212121
Unit cell:
a: 48.74Å b: 57.49Å c: 127.23Å
α: 90° β: 90° γ: 90°
R R work R free
0.142 0.14 0.183
Expression system: Escherichia coli