PDBe 3q25

X-ray diffraction
1.9Å resolution

Crystal structure of human alpha-synuclein (1-19) fused to maltose binding protein (MBP)


Function and Biology Details

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Entry contents:
1 distinct polypeptide molecule
Maltose-binding periplasmic protein; Alpha-synuclein Chain: A
Molecule details ›
Chain: A
Length: 390 amino acids
Theoretical weight: 42.7 KDa
Source organisms: Expression system: Escherichia coli
  • Canonical: P37840 (Residues: 1-12, 13-19; Coverage: 14%)
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
  • nullnull
Gene names: JW3994, NACP, PARK1, SNCA, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P43212
Unit cell:
a: 77.47Å b: 77.47Å c: 172.64Å
α: 90° β: 90° γ: 90°
R R work R free
0.171 0.17 0.196
Expression system: Escherichia coli