PDBe 3py3

X-ray diffraction
2.1Å resolution

Crystal structure of phosphorylated p38alpha MAP kinase

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 14 Chain: A
Molecule details ›
Chain: A
Length: 380 amino acids
Theoretical weight: 43.67 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P47811 (Residues: 1-360; Coverage: 100%)
Gene names: Crk1, Csbp1, Csbp2, Mapk14
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 47.272Å b: 52.284Å c: 168.132Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.184 0.24
Expression system: Escherichia coli