PDBe 3pjj

X-ray diffraction
1.8Å resolution

Synthetic Dimer of Human Carbonic Anhydrase II

Source organism: Homo sapiens
Entry authors: Snyder PW, Kwant RL, Moustakas DT, Mack ET, Butte MJ, Whitesides GW

Function and Biology Details

Reaction catalysed:
H(2)CO(3) = CO(2) + H(2)O. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Carbonic anhydrase 2 Chain: A
Molecule details ›
Chain: A
Length: 259 amino acids
Theoretical weight: 29.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
  • Canonical: P00918 (Residues: 2-260; Coverage: 100%)
Gene name: CA2
Sequence domains: Eukaryotic-type carbonic anhydrase
Structure domains: Carbonic Anhydrase II

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 66.705Å b: 51.132Å c: 80.935Å
α: 90° β: 107.19° γ: 90°
R R work R free
0.222 0.219 0.283
Expression system: Escherichia coli