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Structure of I274V variant of E. coli KatE

Source organism: Escherichia coli K-12
Biochemical function: metal ion binding
Biological process: cellular oxidant detoxification
Cellular component: cytosol

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EC 1.11.1.6: Catalase

Reaction catalysed:
2 H(2)O(2) = O(2) + 2 H(2)O
Systematic name:
Hydrogen-peroxide:hydrogen-peroxide oxidoreductase
Alternative Name(s):
  • CAT
  • Caperase
  • Catalase-peroxidase
  • Equilase
  • Optidase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF18011
Domain description: C-terminal domain found in long catalases
Occurring in:
  1. Catalase HPII
The deposited structure of PDB entry 3p9p contains 4 copies of Pfam domain PF18011 (C-terminal domain found in long catalases) in Catalase HPII. Showing 1 copy in chain A.

PF06628
Domain description: Catalase-related immune-responsive
Occurring in:
  1. Catalase HPII
The deposited structure of PDB entry 3p9p contains 4 copies of Pfam domain PF06628 (Catalase-related immune-responsive) in Catalase HPII. Showing 1 copy in chain A.

PF00199
Domain description: Catalase
Occurring in:
  1. Catalase HPII
The deposited structure of PDB entry 3p9p contains 4 copies of Pfam domain PF00199 (Catalase) in Catalase HPII. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR018028
Domain description: Catalase, mono-functional, haem-containing
Occurring in:
  1. Catalase HPII
IPR041399
Domain description: Large catalase, C-terminal domain
Occurring in:
  1. Catalase HPII
IPR029062
Domain description: Class I glutamine amidotransferase-like
Occurring in:
  1. Catalase HPII
IPR011614
Domain description: Catalase core domain
Occurring in:
  1. Catalase HPII
IPR024712
Domain description: Catalase, mono-functional, haem-containing, clade 2
Occurring in:
  1. Catalase HPII
IPR010582
Domain description: Catalase immune-responsive domain
Occurring in:
  1. Catalase HPII
IPR043156
Domain description: Catalase, mono-functional, haem-containing, clade 2, helical domain
Occurring in:
  1. Catalase HPII
IPR002226
Domain description: Catalase haem-binding site
Occurring in:
  1. Catalase HPII
IPR024708
Domain description: Catalase active site
Occurring in:
  1. Catalase HPII
IPR020835
Domain description: Catalase superfamily
Occurring in:
  1. Catalase HPII

Structure domains

CATH CATH domains
3.40.50.880
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Catalase HPII
The deposited structure of PDB entry 3p9p contains 4 copies of CATH domain 3.40.50.880 (Rossmann fold) in Catalase HPII. Showing 1 copy in chain A.
1.20.1370.20
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Hemocyanin, N-terminal domain
Homology: Hemocyanin, N-terminal domain
Occurring in:
  1. Catalase HPII
The deposited structure of PDB entry 3p9p contains 4 copies of CATH domain 1.20.1370.20 (Hemocyanin, N-terminal domain) in Catalase HPII. Showing 1 copy in chain A.
2.40.180.10
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Catalase HpII, Chain A, domain 1
Homology: Catalase core domain
Occurring in:
  1. Catalase HPII
The deposited structure of PDB entry 3p9p contains 4 copies of CATH domain 2.40.180.10 (Catalase HpII, Chain A, domain 1) in Catalase HPII. Showing 1 copy in chain A.

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