PDBe 3p87

X-ray diffraction
2.99Å resolution

Structure of human PCNA bound to RNASEH2B PIP box peptide

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero hexamer (preferred)
hetero 12-mer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease H2 subunit B Chains: G, H, I, J, K, L
Molecule details ›
Chains: G, H, I, J, K, L
Length: 23 amino acids
Theoretical weight: 2.56 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q5TBB1 (Residues: 290-312; Coverage: 7%)
Gene names: DLEU8, RNASEH2B
Proliferating cell nuclear antigen Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 261 amino acids
Theoretical weight: 28.8 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P12004 (Residues: 1-261; Coverage: 100%)
Gene name: PCNA
Sequence domains:
Structure domains: Proliferating Cell Nuclear Antigen

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 83.108Å b: 81.788Å c: 116.558Å
α: 90° β: 91.47° γ: 90°
R-values:
R R work R free
0.224 0.223 0.248
Expression systems:
  • Not provided
  • Escherichia coli BL21