› 3p4n

X-ray diffraction
2.5Å resolution

Crystal Structure of H2-Kb in complex with the NP205-PV epitope YTVKFPNM, an 8-mer peptide from PV

Released:
DOI: 10.2210/pdb3p4n/pdb
PDB entry 3p4n coloured by chain, front view.
PDB entry 3p4n coloured by chain, side view.
PDB entry 3p4n coloured by chain, top view.
Source organisms:
Entry authors: Gras S, Guillonneau C, Rossjohn J

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-135038 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class I histocompatibility antigen, K-B alpha chain Chains: A, D
Molecule details ›
Chains: A, D
Length: 278 amino acids
Theoretical weight: 32.1 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01901 (Residues: 22-298; Coverage: 80%)
Gene names: H2-K, H2-K1
Sequence domains:
Structure domains:
Beta-2-microglobulin Chains: B, E
Molecule details ›
Chains: B, E
Length: 99 amino acids
Theoretical weight: 11.7 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01887 (Residues: 21-119; Coverage: 100%)
Gene name: B2m
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Nucleoprotein Chains: C, F
Molecule details ›
Chains: C, F
Length: 8 amino acids
Theoretical weight: 1 KDa
Source organism: Mammarenavirus caliense
Expression system: Not provided
UniProt:
  • Canonical: P03541 (Residues: 205-212; Coverage: 1%)
Gene name: N

Ligands and Environments

1 bound ligand:
Ligand ACE 2 x ACE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: AUSTRALIAN SYNCHROTRON BEAMLINE MX1
Spacegroup: P21
Unit cell:
a: 66.19Å b: 90.6Å c: 89.16Å
α: 90° β: 111.11° γ: 90°
R-values:
R R work R free
0.249 0.243 0.308
Expression systems:
  • Escherichia coli
  • Not provided

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