PDBe 3p4k

X-ray diffraction
2.3Å resolution

The third conformation of p38a MAP kinase observed in phosphorylated p38a and in solution

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MAP kinase 14 Chain: P
Molecule details ›
Chain: P
Length: 11 amino acids
Theoretical weight: 1.18 KDa
Source organism: Synthetic construct
Expression system: Not provided
Mitogen-activated protein kinase 14 Chain: A
Molecule details ›
Chain: A
Length: 370 amino acids
Theoretical weight: 42.56 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P47811 (Residues: 1-360; Coverage: 100%)
  • Best match: P47811-4 (Residues: 1-283)
Gene names: Crk1, Csbp1, Csbp2, Mapk14
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P3121
Unit cell:
a: 82.641Å b: 82.641Å c: 123.64Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.179 0.176 0.239
Expression systems:
  • Not provided
  • Escherichia coli BL21(DE3)