PDBe 3oz6

X-ray diffraction
2.37Å resolution

Crystal structure of MapK from Cryptosporidium Parvum, cgd2_1960

Released:
Entry authors: Wernimont AK, Lew J, Lin YH, Sullivan H, Hassanali A, Kozieradzki I, Cossar D, Arrowsmith CH, Bochkarev A, Bountra C, Edwards AM, Weigelt J, Hui R, Neculai AM, Hutchinson A, Structural Genomics Consortium (SGC)

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase Chains: A, B
Molecule details ›
Chains: A, B
Length: 388 amino acids
Theoretical weight: 44.82 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: A3FQ79 (Residues: 4-390; Coverage: 55%)
Gene name: cgd2_1960
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 74.298Å b: 91.746Å c: 119.985Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.231 0.26
Expression system: Escherichia coli BL21