PDBe 3oro

X-ray diffraction
1.9Å resolution

Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 4)


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Serine/threonine-protein kinase PknB Chain: A
Molecule details ›
Chain: A
Length: 311 amino acids
Theoretical weight: 33.52 KDa
Source organism: Mycobacterium tuberculosis H37Ra
Expression system: Escherichia coli
  • Canonical: P9WI81 (Residues: 1-308; Coverage: 49%)
Gene names: MTCY10H4.14c, Rv0014c, pknB
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P212121
Unit cell:
a: 40.598Å b: 51.423Å c: 135.327Å
α: 90° β: 90° γ: 90°
R R work R free
0.195 0.193 0.228
Expression system: Escherichia coli